Some factors can deplete the levels of collagen within the body. Avoiding them could keep the skin healthy for longer.

High sugar consumption: High-sugar diets increase the rate of glycation. Blood sugars attach to proteins to form new molecules called advanced glycation end products (AGEs). AGEs damage nearby proteins and can make collagen dry, brittle, and weak.

Smoking: Tobacco damages both collagen and elastin in the skin. Nicotine narrows the blood vessels in the outer layers of the skin. This compromises skin health by reducing the delivery of nutrients and oxygen to the skin.

Sunlight: Ultraviolet rays in sunlight speeds up collagen break down.   Wear a sunblock. The UV rays in sunlight damage the collagen in the dermis, forming wrinkles.

Autoimmune disorders: Some autoimmune disorders cause antibodies to target collagen.

The aging process causes collagen levels to deplete naturally over time. There is no way to prevent this.  However avoiding tobacco and excess sun exposure and following a healthful dietary and exercise regime can help reduce visible aging and protect collagen. This also keeps the skin, bones, muscles, and joints healthy for longer.